2025 NCAA Football Top 25 Picks Week One

S. Samek

Here are my picks for week one of the 2025 college football season for teams in the top 25. Winners marked in bold.

25 Boise State vs South Florida

Western Illinois vs 12 Illinois

1 Texas vs 3 Ohio State

Syracuse vs 24 Tennessee

Old Dominion vs 20 Indiana

Nevada vs 2 Penn State

Marshall vs 5 Georgia

8 Alabama vs Florida State

South Dakota vs 22 Iowa State

Montana State vs 7 Oregon

Illinois Stat vs 18 Oklahoma

Long Island University vs 15 Florida

North Dakota vs 17 Kansas State

UTSA vs 19 Texas A&M

9 LSU vs 4 Clemson

New Mexico vs 14 Michigan

Arkansas-Pine Bluff vs 23 Texas Tech

Georgia State vs 21 Ole Miss

East Texas A&M vs 16 SMU

Northern Arizona vs 11 Arizona State

Virginia Tech vs 13 South Carolina

6 Notre Dame vs 10 Miami